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Finding worms in your dog’s stool is one of the worst moments of pet ownership, and the first question you ask is whether you can fix it without a vet bill. You usually can. The trick is matching the right active ingredient to the worm you are actually dealing with, because no single dewormer covers every parasite, and the wrong pick wastes days while your dog stays uncomfortable. This guide breaks down nine real options by what they treat, how they dosed, and what owners actually experienced.
This guide is built by comparing the manufacturers’ published specifications and the patterns across verified customer reviews, so you get each pick’s real strengths and trade-offs instead of marketing spin.
You can clear your dog’s worms without a vet visit. Below are the strongest over-the-counter options, sorted by the job they do best. They range from a five-tablet tapeworm specialist to a chewable that handles seven worm species at once. Every pick is available without a prescription. Each entry tells you exactly which worms it targets, so you can choose the one that fits your dog’s weight and situation. This is a practical shortlist of the best dog dewormers.
Top Picks
How To Choose The Best Dog Dewormers
You cannot fix a worm problem you have not identified, so start by asking what you actually saw. Tapeworms show up as flat, rice-like segments near your dog’s tail or in the stool. Roundworms look like thin spaghetti. Hookworms are usually invisible, and you only learn about them when your dog’s stool turns dark or your dog seems weak.
Start With The Active Ingredient, Not The Label
Three ingredients do almost all the work in over-the-counter dog dewormers. Pyrantel pamoate handles roundworms and hookworms. Praziquantel is the tapeworm specialist. Fenbendazole, sold under the Panacur and Safe-Guard names, sweeps through roundworms, hookworms, whipworms and tapeworms over a three-day course. If you do not know which worm you have, a broad-spectrum chewable that pairs pyrantel pamoate with praziquantel covers the most common ones in a single dose.
Match The Dose To Your Dog’s Weight — Exactly
Every product here doses by body weight, and the packaging usually tells you how many tablets or grams to give at each weight band. A 15-pound dog gets one praziquantel tablet from a five-count bottle, while a dog over 60 pounds takes the maximum five tablets. Weigh your dog before you dose. A mid-size dog that falls between bands should step up to the next size packet.
Check The Minimum Age Before You Buy
Age limits vary more than you might expect. The Elanco tapeworm tablets and the Elanco Quad chewables are for dogs over 4 weeks of age. The PetArmor and Worm X Plus chewables start at 12 weeks. The fenbendazole powder products cover puppies from 6 weeks. If you have a very young puppy, that age line decides your shortlist for you.
Decide Between A Single Dose And A Three-Day Course
Chewable dewormers are usually a one-and-done dose, which makes them the easy choice for a busy week. The powder packets that use fenbendazole must be mixed into food and repeated for 3 days in a row. That three-day routine is more work, but it reaches whipworms that the simpler chewables do not list. Choose based on how reliably you can get a full course into your dog’s meals.
Know When To Call The Vet Instead
Over-the-counter dewormers handle the common intestinal worms and nothing more. Heartworm is a different disease, and these products do not prevent it. A dog that is lethargic, vomiting or losing weight needs a fecal test and a diagnosis, not another tablet. Several of these labels say plainly that a sick dog should be seen by a veterinarian before any deworming starts.
Side-by-Side Comparison
| Model | Best For | Worms Targeted | Dose Format | Dog Size Range | Amazon |
|---|---|---|---|---|---|
| Elanco Tapeworm Dewormer★ Best Overall | Tapeworm-only cleanup | 2 tapeworms | 5 tablets | Any, 4 weeks and up | Amazon |
| Worm X Plus 7 Way ChewablesSmall Dog Pick | Small dogs and puppies | 7 species | 2 chewables | 6 to 25 lbs | Amazon |
| PetArmor 7 Way (Large Dogs)Big Dog Workhorse | Big dogs, single dose | 7 species | 2 chewables | 25.1 to 200 lbs | Amazon |
| PetArmor 7-Way Small Dog 6-Count | Multi-dog or repeat dosing | 7 species | 6 chewables | 6.0 to 25 lbs | Amazon |
| Panacur C 4 Gram, 3 Count | Whipworm and broad sweep | Round, hook, whip, tape | 3 powder packets | Treats 40 lbs per packet | Amazon |
| Elanco Chewable Quad Dewormer | Fussy small dogs | 4 species | 4 chewables | 2 to 25 lbs | Amazon |
| Nemex 2 Liquid Wormer | Puppies and litters | Roundworm, hookworm | 2 oz liquid | Dosed by weight | Amazon |
| Safe-Guard Canine 4-Gram 2-Pack | Pour-over-food dosing | Round, hook, whip, tape | 6 powder packets | 40 lbs per packet | Amazon |
| Panacur C 12 Gram, 4-Pack | Kennels and multi-dog homes | Round, hook, whip, tape | 12 powder packets | 40 lbs per packet | Amazon |
Detailed Reviews
1. Elanco Tapeworm Dewormer 5 Count
Our pick — 4.5+★ from 5,500+ verified ratings; the strongest balance of quality and price.
The five-tablet bottle that turns a tapeworm scare into a one-pill fix
Tapeworms are the most common worm owners actually see, because those rice-like segments leave the body on their own, and praziquantel is the ingredient that kills them. Elanco’s bottle is built around exactly one job: 5 tablets of praziquantel, dosed by weight, for the two tapeworm species that most often infect dogs — Dipylidium caninum and Taenia pisiformis. A 5-pound dog takes half a tablet. A dog over 60 pounds takes the full 5. Fasting is not required, and neither is a prescription.
What earns this pickup its place at the top is follow-through. The tablets work quickly enough that owners describe the problem clearing within a day, and the dosing chart is printed on the box so you are not guessing at midnight. At 0.8 ounces, the bottle fits in a travel kit or a kennel drawer. At 5 tablets it holds 2.5 times the count of the Worm X Plus 2-pack, so a single bottle covers a full large-dog course without a second trip to the store.
The honest limit is scope. Praziquantel (a tapeworm-killing drug) is a tapeworm killer and nothing else. If your dog has roundworms or hookworms, this bottle will not touch them. Weigh your dog before you order, too. A large dog can use all 5 tablets in a single dose. That surprises owners who assume one bottle means one session. Buyers report “Bought after adopting shelter dog with worms; worked immediately, dog took pills without issue, worms cleared and no recurrence since.” One bottle covers a full large-dog course, so a single order handles the whole tapeworm cleanup.
Where the bottle wins
- 5 tablets per bottle, enough for a 60-pound-plus dog in one dose
- Praziquantel targets the two tapeworm species owners see most
- Tablets can go straight in the mouth or be crumbled into food
- No fasting required, no prescription needed
What it does not solve
- No activity against roundworms, hookworms or whipworms
- A large dog can consume a whole bottle in one dose
- Dosing chart is not shown clearly in the listing photos
Reach for it if: you have spotted flat tapeworm segments and want a single targeted pill your dog will swallow without a fight.
Pass if: you are seeing thin, spaghetti-like worms instead — those are roundworms, and this bottle is not the tool for them.
2. Worm X Plus 7 Way De-Wormer Small Dogs
Two chewables that sweep seven worm species out of a small dog
If you are not sure which worm you are looking at, this is the widest net you can cast without a prescription. Worm X Plus pairs pyrantel pamoate (a deworming drug) with praziquantel (a tapeworm killer) — the same two actives used in vet-brand dewormers. It covers two tapeworms, two roundworms and three types of hookworms. That is seven species in a small chewable. The weight rule is straightforward: one tablet for a 6 to 12 pound dog, two for a dog between 12.1 and 25 pounds, and nothing at all for a dog above 25 pounds because that size needs a different product.
The chewable format is the practical win here for a dog that fights pills. You can hand it over with food or without, and the flavor is designed to be eaten rather than hidden. The 2-pack is the smallest commitment in this lineup. That suits a household that only needs a single dose for one small dog. Owners mention “Seemed to clear the hook worm infestation. My dog ate it just like a treat.” The carton measures 8.75 inches tall and 5.38 inches wide, versus 2 inches on each side for the Elanco tapeworm bottle. That is a physical reminder that this box contains a full dosing card rather than a pocket vial.
Two things to sort out before you order. The first is age — this is for dogs 12 weeks and older, so a younger puppy is out. The second is stomach reaction. Most dogs tolerate it cleanly, but a fair share of reviews describe vomiting afterward, so give it when you are home to watch your dog rather than right before you leave. If you have a large dog, skip this entirely and look at the PetArmor large-dog chewable instead.
Why it earns a slot: seven species in two beef-style chewables, with no prescription and a weight chart that covers the whole small-dog range. Seven species in a two-chewable dose is why it makes the shortlist for any dog under 25 pounds.
The catch to plan around: the tablet count is tight. Two chewables is one dose for a dog in the 12.1 to 25 pound band, so a second dog or a repeat treatment means a second order.
Built for: a small dog or puppy over 12 weeks with an unidentified worm problem.
Not for: a dog over 25 pounds, or a puppy younger than 12 weeks.
3. PetArmor 7 Way De-Wormer for Large Dogs (Over 25 lbs)
The two-chewable dose that covers a Great Dane as easily as a Labrador
Here is the number that sets this apart from every small-dog product above: it is safe for dogs from 25.1 pounds all the way to 200 pounds. The dosing steps up with the dog — 1 tablet for 25.1 to 50 pounds, 2 for 50.1 to 100, 3 for 100.1 to 150, and 4 for 150.1 to 200. The pack holds 2 chewables, so a dog in the 50-to-100 pound band gets its full course from one packet. Big dogs are exactly where single-dose dewormers usually fall short, because they eat through a small bottle in one go.
The active pair is the same proven combination as the Worm X Plus: pyrantel pamoate (a deworming drug) plus praziquantel (a tapeworm killer), covering 2 tapeworms, 2 roundworms and 3 hookworms. What people come back for is how little it disturbs the dog. One owner’s experience sums up the best-case version: “I found worms in my dog’s stool, so I gave her this dewormer as directed. After using it, the worms were gone and I haven’t noticed any since. She tolerated it really well too—no upset stomach, vomiting, or other issues.” The chewable is small — the package weighs just 0.317 ounces versus 0.8 ounces for the Elanco tapeworm bottle — so a fussy large dog can take it wrapped in peanut butter.
The one thing to know is that this is sized for a single dose, not a repeat course. If you are treating more than one large dog, or expect to retreat, the same brand sells a 6-count small-dog pack that owners of multi-dog homes tend to prefer for volume. And as the label itself says, if a single course does not clear the problem, a vet visit with a fecal test is the right next step rather than a second blind dose.
Standout spec: a weight ceiling of 200 pounds. That is the widest range on this list, and it means one product covers everything from a medium terrier to a giant breed.
Caveat worth noting: a 2-count pack is a single treatment for one large dog. Multi-dog homes will go through it fast.
Pick this when: your dog is over 25 pounds and you want a vet-quality single dose without a prescription.
Look elsewhere when: you have a small dog under 25 pounds — this one is not dosed for it.
4. PetArmor 7-Way Dog Dewormer Small 6-25 lbs, 6-Count Chewable
Six chewables that cover two small dogs, or one dog twice
This is the same 7-way formula as the large-dog PetArmor, repackaged for the 6 to 25 pound window and sold in a 6-count bottle. The math works out in your favor: a 6 to 12 pound dog takes 1 tablet and a 12.1 to 25 pound dog takes 2. So six chewables covers three full treatments for a mid-size dog or a full round for a small pack. It is safe for puppies 12 weeks and older. It uses the same pyrantel pamoate (a deworming drug) and praziquantel (a tapeworm killer) pairing that reaches 2 tapeworms, 2 roundworms and 3 hookworms.
Where the larger format often overshoots for a small dog, this one lands right on the weight band. Owners like the beef-flavored chew. One summed up the convenience plainly: “The chewables are super convenient and fast-acting, so dosing is a breeze. No prescription needed, which is a huge plus. Easy to administer and my pup actually eats them.” The recurring note across reviews is stomach sensitivity — a soft stool or a mild upset within hours of the dose. So it is worth planning to give it on a day when you can keep an eye on your dog rather than right before a car trip.
Compared to the 2-count Worm X Plus, this bottle holds three times the tablets at the same weight band, which is why it makes more sense for anyone who expects to treat more than once. The packaging is a little larger — 5.63 inches tall versus 8.75 on the Worm X Plus carton — but the bottle itself is easy to store in a bathroom cabinet. If you only have one small dog and are not planning a repeat, the smaller pack is the simpler choice.
Why the 6-count makes sense
- Six chewables cover three doses for a mid-size small dog
- Same 7-species coverage as the large-dog version
- Beef flavor that dogs accept without hiding it in food
- Puppy-safe from 12 weeks
What to expect going in
- Some dogs get a soft stool in the hours after dosing
- Not dosed for dogs above 25 pounds
- Package is bigger than a small-dog bottle needs to be
Best match: a small dog or two that needs more than one treatment, or a puppy household dosing on a schedule.
Look at the 2-count instead if: you only need one dose for one dog and want the smallest pack available.
5. Panacur C Canine Dewormer (Fenbendazole), 4 Gram, 3 Count
Three powder packets that reach the whipworms the chewables miss
The active ingredient here is fenbendazole, and it does something none of the chewables above can claim on their label: it targets whipworms alongside roundworms, hookworms and tapeworms. It also reaches Giardia, which is not a worm at all but a parasite owners often mistake for one. Each 4-gram packet treats a 40-pound dog for one day, and the label is clear that the daily dose repeats for 3 days in a row. This 3-count box is a complete course for a 40-pound dog, or one day’s worth for a dog that needs 2 packets.
Dosing is where this product lives or dies, and it calls for a little patience. You mix the powder into a small amount of your dog’s usual food and make sure the whole medicated portion gets eaten. Moistening dry kibble helps the powder stick. That extra step is the trade-off for coverage the simpler chewables cannot match. One owner’s experience captures the routine well: a 40-pound dog got 1 packet a day and a 70-pound dog got 2, both mixed into Greek yogurt for 3 days, and the worms were cleared by the end of the course. The same owner reported both dogs still clear a month after the course.
The powder is nearly tasteless and odorless, so a fussy dog is less likely to turn it down than a tablet. The packet form also means no pill to hide, which is a real advantage for a dog that has learned to spit out capsules. What it will not do is cover heartworm, and it cannot be given to a dog that is already sick — the label says to get a vet diagnosis first. For most households, the 3-day routine is the price of the widest coverage on this list.
Why it stands out: whipworm coverage and Giardia reach in a form the chewables do not match. For a dog with chronic loose stools and no obvious tapeworm segments, this is the ingredient worth asking about.
Trade-off to accept: the 3-day repeat is more effort than a single chew, and the powder must be mixed thoroughly into food your dog will finish.
Choose this if: your dog has whipworm or persistent GI trouble the chewables have not touched, and you can commit to three days of food mixing.
Skip if: you want one-and-done dosing, or you are treating a dog that is already unwell — that calls for a vet first.
6. Elanco Chewable Quad Dewormer Small Dogs 4 Tablets
Four beef chewables for the small dog that hates taking medicine
The name tells you the coverage: Quad means four, and the four here are tapeworms, roundworms, hookworms and whipworms. That whipworm line is the differentiator against the 7-way chewables, which handle three hookworm types but no whipworm. The tablets are beef-flavored and shaped to be eaten like a treat, and they are safe for dogs over 4 weeks of age in the 2 to 25 pound band. Four tablets is a useful quantity, since most small dogs in that range need one to one and a half per dose, leaving a spare for a later treatment.
The flavor is genuinely the headline, not just a detail. Dogs that usually fight a pill tend to take this one straight from the hand, and one owner described a 12-pound chihuahua eating the bone-shaped chews readily while the rest of the tablets were saved for later. There was one loose stool within 24 hours, then the dog was fine. Expect a possible loose stool in the first 24 hours, then normal stools. The small-dog sizing keeps the tablet from being a chore for a dog that would choke on a bigger one.
One point of caution is odor. The beef flavor that dogs love is strong to human noses, so keep the bottle sealed and away from a kitchen shelf. A few owners also find the price on the higher side compared to buying directly from a pet store, so it pays to check both places before you commit. And no product in this lineup prevents heartworm — this one included.
What wins owners over: a beef chew a fussy small dog will eat without a fight, plus whipworm coverage the 7-way chewables do not list.
Small gripe to know: the beef smell is strong, and a few dogs get a loose stool in the first day.
Fits well if: you have a small dog under 25 pounds that turns its nose up at pills, and you want four-worm coverage in one chew.
Not the one for: a large dog — this is dosed strictly for the 2 to 25 pound range.
7. Nemex 2 Liquid Wormer, 2 oz
The liquid a whole litter will lap up without a wrestling match
Puppies are the hardest patients in the worm-fighting business. They cannot swallow a tablet, they squirm, and a litter multiplies the problem by every pup. Nemex 2 solves the mechanics with a liquid that carries 4.54 mg of pyrantel pamoate per ml, targeted at large roundworms and hookworms — the two worms newborn puppies pick up from their mother’s milk. It is safe and palatable, and it is dosed by weight in milliliters rather than tablets.
The palatability is the whole game here. Puppies that refused a rival brand took this one straight from a palm, and one owner cleared worms in 11 puppies with the flavor doing most of the work. The same pattern holds across reviews: dogs and puppies lick it up rather than needing to be dosed with a syringe, which turns a two-person wrestling match into a one-person job. The 2-ounce bottle holds enough for a small litter at the weight the label covers.
The scope is intentionally narrow. This is roundworm and hookworm only — no tapeworm, no whipworm. If you see flat segments near your dog’s tail, you need a praziquantel product instead, and the Elanco tapeworm tablets are the direct answer. For a breeder or a new puppy owner facing the standard roundworm issue, though, the liquid format is the reason to choose this over everything else here.
The case for it: liquid dosing makes a litter manageable, and pyrantel pamoate is the right active for the roundworms and hookworms puppies usually carry.
Know the limit: two worm types only. This will not touch tapeworm or whipworm.
Made for: a puppy or a whole litter that needs roundworm and hookworm treatment without a pill fight.
Wrong tool for: a tapeworm problem, or a dog that needs broad multi-species coverage.
8. Safe-Guard Canine Dewormer Large Dogs 4-Gram
Six powder packets that turn a big dog’s dinner into a deworming dose
Each packet treats a 40-pound dog for one day, and the daily dose repeats for 3 days — so the whole thing is a full course for a 40-pound dog, or three days for two dogs. The active ingredient is fenbendazole, and the label names roundworms, hookworms, whipworms and tapeworms, plus it covers Giardia in real-world use.
The reason to choose Safe-Guard over the Panacur version depends on how it mixes. The granules are nearly tasteless and odorless, so a picky dog notices almost nothing when the powder goes into damp food. Owners who have used it for years describe it as a go-to when their dogs get into something they should not. The packet format means no pill to hide. The dosing is the same 50 mg per kg of body weight as the Panacur, so if you have used one you already know the routine.
Value is the split opinion here. Some owners find the double pack reasonably priced for a multi-dog household, while others consider it on the pricier side compared to the single-box Panacur. If you have one 40-pound dog and only need one course, a smaller box does the same job. If you have two large dogs or expect to retreat, the 6-packet pack saves you a second order. The same rule applies as with any fenbendazole product: do not use it on a dog that is already sick without a vet’s diagnosis.
What makes it useful
- 6 total packets in the double pack — a full course for a 40-pound dog or two
- Whipworm and tapeworm coverage the chewables do not always list
- Nearly tasteless granules mix into damp food without a fuss
What to weigh
- Higher upfront cost than a single 3-packet box
- Requires a 3-day repeat rather than one dose
- Not effective against heartworm
Great fit for: a two-large-dog household that wants broad coverage and a full course in one box.
Consider the smaller box if: you have one dog and only need a single 3-day treatment.
9. Panacur C Canine Dewormer, 12 Grams, Four 4-Gram Packets
Twelve packets for the household that deworms on a calendar
The package is 4 boxes, each holding 3 packets of 4 grams, which adds up to 12 packets in total. Each packet is a daily dose for a 40-pound dog, and the routine repeats for 3 days, so a single box covers one full course and the whole set covers four. The ingredient is fenbendazole, the same broad-spectrum dewormer as the 3-count box, reaching roundworms, hookworms, whipworms and tapeworms. It is safe for dogs 6 weeks and older, including pregnant bitches.
The reason to buy the big box is a simple one: kennels and multi-dog homes go through packets fast. An owner who says “Panacure C is what we use in our kennel and it’s never let us down” is describing exactly the buyer this format serves. If you are treating more than one dog, or following a repeat-deworming schedule across the year, buying the 12-packet set removes the “ran out mid-course” problem entirely.
One thing to look for is authenticity. Counterfeit packets exist, and the genuine product has the manufacturer’s expiration date imprinted into the back of the pouch. Check that date the moment the box arrives. If it is missing or printed as a sticker, the packet is not what it should be. The label is also explicit about a limit: do not deworm a dog that is already sick — get a diagnosis first, then treat.
Where it fits: a kennel, a breeder, or a home with several dogs that deworms on a fixed schedule. Twelve packets ends the last-minute reorder.
The honest note: it is a lot of course if you have one dog. The smaller 3-count box would cover a single treatment.
Pick it up if: you treat multiple dogs or repeat courses through the year and want the whole routine in one box.
Overkill for: a single dog with a one-off tapeworm problem — the smaller pack is the right size.
Know the Specs
Active Ingredient — What It Kills
Every product here is defined by its active ingredient, not its brand name. Pyrantel pamoate targets roundworms and hookworms. Praziquantel targets tapeworms. Fenbendazole, the ingredient in Panacur and Safe-Guard, sweeps through roundworms, hookworms, whipworms and tapeworms over a multi-day course. Match the ingredient to what you actually saw in the stool, and you avoid buying a tapeworm pill for a roundworm problem.
Dose Format — Chewable vs Powder vs Liquid
The format decides how much work treatment takes. Chewables are a one-and-done dose a dog can eat like a treat. Powder packets must be mixed into wet or dampened food and repeated over 3 days. Liquid is the only practical option for a very young puppy or a litter that cannot take a tablet. Pick the format that fits your dog’s willingness to eat medicine, not just the ingredient list.
Weight Range — Read the Dosing Bands
Every product doses by body weight, and the bands do not overlap. A 25-pound dog sits at the top of a small-dog product and the bottom of a large-dog one. A 60-pound dog taking a five-count praziquantel bottle uses the whole bottle in one dose. Weigh your dog on a scale before ordering. If the weight falls between two dosing sizes, the label advice is to step up to the next size packet.
Minimum Age — Puppies Change the List
Age limits are not uniform across the category. The Elanco products start at 4 weeks. The PetArmor and Worm X Plus chewables require 12 weeks. The fenbendazole powders are safe from 6 weeks. If you are treating a very young puppy, that one line on the label decides your shortlist before any other feature matters.
Heartworm Is Not Covered
None of the products in this lineup prevent heartworm, which is a separate disease spread by mosquitoes. If your dog needs heartworm prevention, that is a different medication. These products treat intestinal worms only. A dog that is coughing, lethargic or losing weight needs a vet visit for a proper diagnosis rather than another over-the-counter tablet.
Genuine Product and Expiration Dates
Counterfeit packets exist in this category. The genuine Panacur and Safe-Guard pouches have the manufacturer’s expiration date imprinted directly into the back of the pouch rather than printed on a sticker. Check that date when the box arrives. If it is missing or looks pasted on, return the product before you dose your dog.
Common Questions
Can I use a dog dewormer on my cat if I adjust the dose?
How long does it take for a dog dewormer to work?
Do these dewormers prevent heartworm?
Can I give my dog a dewormer if it is already sick or has diarrhea?
What is the difference between a 7-way dewormer and a 4-way dewormer?
How often should I deworm my dog?
Can puppies take these dewormers?
Why did my dog vomit after taking a dewormer?
Will a dewormer clear tapeworms without also treating fleas?
Is it safe to give two different dewormers at the same time?
How do I know if my dog has whipworm instead of roundworm?
The Bottom Line
The right dewormer is the one that matches the worm you actually have, and the Elanco Tapeworm Dewormer does that single job better than anything else here. It handles the tapeworm species owners see most, in a five-tablet bottle that covers a large dog in one dose, and thousands of owners have confirmed it clears the problem quickly. If you cannot identify the worm, the PetArmor 7 Way for large dogs casts the widest net at the widest weight range — up to 200 pounds. And for the dog with chronic loose stool that the chewables never fixed, the Panacur C 4 Gram is the one to reach for, because fenbendazole is the only ingredient on this list that lists whipworm coverage. Identify the worm first, pick the ingredient that kills it, then match the weight band — that order beats any brand name.
How we choose
We do not accept paid placement. Every pick is matched to a real buyer and a real use-case; we do not hands-on test units.
Sources
Specifications: manufacturer listings and product documentation. Review insights: verified customer reviews, as of October 2026. Pricing: not shown on this page (it changes often); check the current price via the retailer link.
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